Scaling Biotech

Jesse Johnson
Exploring organizational and technology strategy for growing research platforms.
Created 11 Nov 2020
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  • The first "why" of your story
    29 Sep 2021 • < 1 min read • 1 0
    I'm writing this email because I want you, dear reader, to change the way you communicate technical information with colleagues. In particular, I want you to start thinking carefully about what you wa...
  • Communicating with Stories
    22 Sep 2021 • < 1 min read
    Scaling a Biotech research platform requires getting many people from a wide range of backgrounds and mindsets to adopt a common vision and plan. The more variation and inconsistency about what your c...
  • Seeing the hard part
    15 Sep 2021 • < 1 min read
    It’s a mistake I’ve made more times than I care to admit. As you get to the end of a project, ready to tie up a last few loose ends, instead of a smooth slope down to the finish line, you see another ...
  • The Operational Stack
    08 Sep 2021 • < 1 min read
    I’ve written previously about how it’s nearly impossible to roll out a software system for an organization until the processes that it supports are defined. More recently, I’ve realized that this is o...
  • Constructive Conflict
    01 Sep 2021 • < 1 min read
    Scaling a biotech research platform requires finding the ideal balance along a number of different tradeoffs. But how do you know if you’ve found it? Data access is a good example: How do you make sur...
  • Distributed Metaphors
    25 Aug 2021 • < 1 min read
    Scaling a biotech research platform requires combining a collection of different software systems and components into a single coherent whole, aka a Chimera Data Platform. To keep this system maintain...
  • The crystallized amoeba
    18 Aug 2021 • 1 min read
    There are two closely related ideas that I’ve written about in this newsletter, that when combined lead to a mental model I call the crystallized amoeba. The first idea is that on the flexibility/cons...
  • On flexibility, consistency and schema enforcement
    11 Aug 2021 • < 1 min read
    Scaling a biotech research platform requires maintaining enough flexibility to collect data in an always-changing environment, but enough consistency to ensure that the collected data is usable. Makin...
  • Are you buying the software or the schema?
    04 Aug 2021 • < 1 min read
    If you’ve used enough Enterprise software, you probably noticed that they tend to have the same types of components: Tables, forms, lists, maybe a few others. What makes these applications different i...
  • The Blind Philosopher's Database
    28 Jul 2021 • < 1 min read
    Scaling a biotech research platform requires an organization to define and optimize the flow of data, which can be broken down into three questions: 1. What tasks do we need data for (and what data do...
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